Comparative analysis of gene expression profiles of papillary thyroid microcarcinoma and papillary thyroid carcinoma
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چکیده
منابع مشابه
Comparative analysis of gene expression profiles of papillary thyroid microcarcinoma and papillary thyroid carcinoma.
PURPOSE Papillary thyroid carcinomas (PTCs) measuring 1.0 cm or less were separately defined as papillary thyroid microcarcinomas (PTMs) by the World Health Organization, emphasizing on their benign behavior. However, some reported that PTMs may have aggressive behavior, can cause regional, or even distant metastases. But till now, the characteristics of PTMs were only reviewed and described by...
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Background: Papillary thyroid carcinoma (PTC), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. The objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in PTC with regard to age, gender, tumor size and lymph node involvement. Methods: Immunohistochemical stains were performed on 92 tissue bl...
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Thyroid cancer is the most common endocrine malignancy. This study surveys the pathologic characteristics of thyroid cancerin Mashhad and study of papillary carcinoma in more detail. In this retrospective study, 108 out of 197 cases of thyroid cancer were papillary in type (55%), with female to male ratio of 1.91 which is lower than current reports. The age at the time of diagnosis ranged ...
متن کاملGene expression in papillary thyroid carcinoma reveals highly consistent profiles.
Papillary thyroid carcinoma (PTC) is clinically heterogeneous. Apart from an association with ionizing radiation, the etiology and molecular biology of PTC is poorly understood. We used oligo-based DNA arrays to study the expression profiles of eight matched pairs of normal thyroid and PTC tissues. Additional PTC tumors and other tissues were studied by reverse transcriptase-PCR and immunohisto...
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AIM OF THE STUDY The treatment for papillary thyroid microcarcinoma (PTMC), which is a tumor measuring less than 1 cm, is still a subject of controversy. The aim of this study is to retrospectively evaluate the patients diagnosed with PTMC in terms of their clinical and histopathological features. MATERIAL AND METHODS A total of 153 consecutive patients with PTMC were treated, and their clini...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2010
ISSN: 0973-1482
DOI: 10.4103/0973-1482.77103